Gout and Kidney Disease | Taking Care Of Your Body

Gout and kidney disease, can kidney disease increase the risk of developing gout? Kidney disease can increase the risk of developing gout because the kidneys play a key role in removing uric acid from the body. Uric acid is a waste product that is produced when the body breaks down purines, which are substances found in many foods and in the body's own tissues. Normally, the kidneys filter uric acid out of the blood and excrete it in the urine.

However, in people with kidney disease, the kidneys may not be able to filter enough uric acid, leading to higher levels of uric acid in the blood. When the levels of uric acid in the blood are too high, the uric acid can form crystals in the joints, leading to the painful symptoms of gout. In addition, some medications that are commonly used to treat kidney disease, such as diuretics, can also increase the levels of uric acid in the blood and contribute to the development of gout.

How Your Body Develops Gout From Kidney Disease

Kidney disease that can lead to gout can have several effects on the body. The kidneys play a crucial role in removing waste products and excess fluids from the body, regulating electrolyte balance, and producing hormones that help to control blood pressure and stimulate red blood cell production.

When the kidneys are damaged or not functioning properly, these processes can be disrupted, leading to a range of symptoms and complications. In addition, when the kidneys are not functioning properly, they may not be able to remove enough uric acid from the body, leading to higher levels of uric acid in the blood. This can contribute to the development of gout, which is a type of arthritis that results from the buildup of uric acid crystals in the joints.

Gout can cause severe pain, swelling, and stiffness in the affected joints. Other symptoms and complications of kidney disease can include:

  • Fluid retention and swelling in the legs, ankles, or feet
  • Fatigue and weakness
  • Shortness of breath
  • High blood pressure
  • Anemia (low red blood cell count)
  • Bone disease
  • Nerve damage
  • Decreased appetite and weight loss


 It's important for people with kidney disease to work closely with their healthcare providers to manage their condition and prevent or minimize complications such as gout. This may involve making lifestyle changes, taking medications, and undergoing dialysis or kidney transplant if the kidney disease is severe.

What Symptoms Do You Develop From Kidney Disease That Lead To Gout?

Kidney disease can lead to gout by causing an accumulation of uric acid in the blood. Uric acid is a waste product that is produced when the body breaks down purines, which are substances found in many foods and in the body's own tissues. Normally, the kidneys filter uric acid out of the blood and excrete it in the urine. However, in people with kidney disease, the kidneys may not be able to filter enough uric acid, leading to higher levels of uric acid in the blood.

When the levels of uric acid in the blood are too high, the uric acid can form crystals in the joints, leading to the painful symptoms of gout. The symptoms of gout that can result from kidney disease are the same as those that can occur in people without kidney disease. These symptoms can include:

  • Sudden onset of intense pain in a joint, most commonly the big toe, but also the ankle, knee, elbow, wrist, or fingers
  • Swelling, redness, and warmth around the affected joint
  • Stiffness and limited range of motion in the affected joint
  • Skin around the joint may be itchy, flaky, or peeling

In addition to the symptoms of gout, kidney disease can cause a range of other symptoms and complications. These can include:

  • Fatigue and weakness
  • Swelling in the legs, ankles, or feet
  • Shortness of breath
  • High blood pressure
  • Anemia (low red blood cell count)
  • Bone disease
  • Nerve damage
  • Decreased appetite and weight loss

If you are experiencing any of these symptoms, visit your healthcare provider for an evaluation and appropriate treatment.

How Can You Prevent Getting Gout While Having Kidney Disease?

If you have kidney disease, there are several things you can do to reduce your risk of developing gout:

  1. Manage your diet: Limiting the intake of purine-rich foods can help lower the levels of uric acid in the blood. Foods that are high in purines include red meat, organ meat, shellfish, and certain types of fish. You may also want to limit your intake of alcohol, especially beer, as it can increase uric acid levels.

  2. Stay hydrated: Drinking plenty of water and other fluids can help to flush excess uric acid out of the body. Aim for at least 8-10 glasses of water per day.

  3. Take medications as prescribed: If you have been prescribed medications for your kidney disease or other conditions, be sure to take them as directed by your healthcare provider. Some medications, such as diuretics, can increase uric acid levels and contribute to the development of gout. Your healthcare provider may adjust your medications or prescribe additional medications to help manage uric acid levels.

  4. Maintain a healthy weight: Being overweight or obese can increase the risk of developing gout. If you are overweight, losing weight can help to reduce your risk.

  5. Exercise regularly: Regular exercise can help to maintain a healthy weight, improve kidney function, and lower the risk of gout. Aim for at least 30 minutes of moderate-intensity exercise, such as brisk walking or cycling, most days of the week.

It's important to work closely with your healthcare provider to manage your kidney disease and prevent or manage any complications such as gout. They can help you develop a plan that is tailored to your specific needs and medical history.

When Should You Seek Medical Attention For Gout And Kidney Disease?

If you have gout and kidney disease, it's important to seek medical attention if you experience any of the following symptoms or complications:

  1. Severe pain: If you experience sudden and severe pain in a joint, especially if it's accompanied by swelling, redness, and warmth, you should seek medical attention. This may be a sign of a gout flare-up.

  2. Worsening kidney function: If you have kidney disease and notice a decrease in urine output, swelling in the legs or feet, or increased fatigue or weakness, you should contact your healthcare provider. These may be signs of worsening kidney function.

  3. Side effects from medications: If you experience any side effects from medications prescribed for your gout or kidney disease, such as allergic reactions, rash, or difficulty breathing, you should seek medical attention immediately.

  4. Fever or infection: If you have a fever or signs of an infection, such as chills, sweats, or a wound that is red or swollen, you should seek medical attention. These symptoms may indicate a serious infection that requires treatment.

See your healthcare provider regularly for check-ups and monitoring of your kidney function and uric acid levels. They can help you develop a plan to manage your gout and kidney disease and prevent or minimize complications.